WHAT IS CBD

Based on extensive 2-year assessments by an Independent Scientific Committee, the WHO guidelines are the first of its kind since the Single Convention on Narcotic Drugs was passed in 1961.

One of the WHO guidelines focused on CBD medicines and pharmaceuticals. CBD per se is not included in the lists of the Drug Control Treaties. But THC is.

On the 2nd of December 2020, the United Nations (UN) amended the act by recognising the therapeutic properties of Cannabis sativa plant by-products. CBD is no longer specifically listed in the 1961, 1971 or 1988 UN Drug Control Treaties. However, if processed as an extract or solution, it is controlled under Schedule I of the 1961 Single Convention on Narcotic Drugs.

WHAT IS CANNABIDIOL AND WHAT IS IT FOR?

Scientific studies have shown that CBD gradually relieves skin symptoms related to atopic-prone skin such as psoriasis, allowing patients to instantly obtain relief.

Cannabidiol, one of the most important components of the Cannabis sativa plant, as it contains numerous therapeutic effects, is definitely here to stay as its properties make this substance one of the best natural remedies for our body. The Cannabis plant produces a resin that contains compounds such as terpenophenolics and cannabinoids, as well as other compounds of plant origin, such as terpenes and flavonoids. The highest levels of cannabinoids are found in the female flowers of the plant.

Cannabinoids trigger certain receptors throughout the body that produce biochemical changes, particularly in the central nervous system and the immune system, as humans possess endocannabinoid receptors. In fact, commonly available marketed cannabinoids (CBD), such as Dronabinol and Nabilone, are licensed drugs for the treatment of cancer-related side effects.

THE FRAMEWORK
OF THE
ENDOCANNABINOIDE
SYSTEM (ECS)

The ECS is made up of three types of building blocks:

1. Endocannabinoids, substances produced by our own organism, similar to the active ingredient in hemp. Its main purpose is to trigger the cannabinoid receptors, which are proteins in the cell membrane that pass on information to the cell that is loaded with "wellbeing".

2. Neurobiological cannabinoid receptors, specific for detecting cannabinoids. There are two types of receptor: type 1 and type 2 (CB1 and CB2)*.

3. Enzymes that synthesise and break down cannabinoids, thus limiting the duration of their action. In other words, they determine the "expiry time" of that wellbeing.

The CB 1 receptor was first identified in the brain in 1988. The CB 2 receptor was identified in 1993. The highest level of CB 2 receptor is found in B lymphocytes and natural cytolytic lymphocytes, or in simpler terms it means they are mostly located in immune cells and, when activated, can modulate immune cell migration.

Endocannabinoids, also called endogenous cannabinoids, appear to play a vital role in pain modulation, movement control, eating patterns, mood, bone growth, inflammation, neuroprotection (nervous system) and memory.

WHERE DOES THE
ENDOCANNABINOID
SYSTEM (ECS) ACT?

WHAT ARE
CBD CREAMS
USED FOR?

Continuing to talk about these products, one of the worries that often arises is about their use, which goes far above and beyond a simple moisturizer for the skin. In that sense, and although CBD creams can also help us improve the appearance of our skin, its use is mainly therapeutic and not so much aesthetic. Therefore, we will have to choose the option that best suits us.

Unfortunately, we are not able to give a general recommendation to everyone, as it goes without saying that it is not the same as treating muscle pain as it would be to treat a rash or atopic dermatitis. However, both their use and application are not a problem, making these creams extremely useful to incorporate into our daily routine.

Although topical use of Cannabis sativa dates all the way back to ancient populations, such as Egyptian or Chinese, to this day, further research is still needed on how it can improve skin conditions and muscle pain when applied directly to the skin.

BENEFITS
OF USING
CBD CREAMS

The benefits associated with cannabidiol (anti-inflammatory; calming; effective against pain; or antipsychotic, among others) can also be obtained when directly applied to the skin. The different compounds that we often find in CBD creams and ointments make them more favourable as they are best absorbed by the skin. Thus, making them especially interesting from a dermatological point of view. Remember that cannabinoids have a very low toxicity for our body, meaning that there are hardly any side effects (unlike what happens with most drugs) or that these are very mild and do not pose any harm or risk.

In addition, its effect is only superficial and despite the fact that cannabidiol is absorbed through the skin, it does not reach our blood and, therefore, does not reach the central nervous system. If we add to that to the fact that CBD does not have a psychotropic or psychoactive effect (unlike THC, another of the most important compounds in cannabis) and that its application is limited to a specific area or areas of our body, these products are shown as a very sought-out option for those who are simultaneously taking other types of treatments, even if those treatments are cannabidiol based too.

CONTRAINDICATIONS

With saying this, even though these CBD products, such like the creams and ointments do not at first display any serious side effects it does not mean that they have no physical side effects. The cannabinoids are known for their therapeutic use and, therefore, its use should be supervised by a professional.

It is also important to recognise that during these stages of life such as, pregnancy and lactation, infants and adolescents, as well as elderly people, it is advisable to always take precaution before applying any of these creams.

What we do know is that the CBD is known not to reach the blood stream. However, among these stages, they can be more susceptible and vulnerable to foreign bodies.

Therefore, it is always vital to consult on its use with a doctor or pharmacist.

THERAPEUTIC
USES OF CBD.
WHAT IT'S
USED FOR

Cannabidiol (CBD) is one of the most studied cannabinoids. Without psychoactive properties as it does not act through the brains CB1 receptors that are responsible for our psych activity and its multiple therapeutic properties- antioxidants, analgesics, anti-inflammatory, anticonvulsant, anxiolytic or antitumor, among others—we know that it can treat various diseases.

SKIN
INFLAMMATORY
DISEASES

Chronic diseases such as dermatitis, inflammation of the skin; autoimmune psoriasis, common or worse off cases of acne, clustering of pimples or spots, pustules (small cavities full of pus) and scars.

Therapeutic effects on inflammatory skin diseases (study, study, study):

Anti-inflammatory
Moisturizer
Decrease in redness
Reducing flaking
Soothing itchiness

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